Getting RAM error messages saying files can't be opened

This is happening even when I have closed out of all other applications. I have 8GB of ram and 256GB flash storage. The specific file says it is 85.2 MB, this just seems so small compared to what my computer says it can handle. I have a RAM cleaner to help stop my computer from crashing when it gets too low, when I get the error messages it seems to say there is almost always at least 5 GB of RAM available. Any suggestions as to what the problem might be? Am I just working with files that are too large and need more RAM?

BubbleBug,
You may have suffered some kind of corruption; that may also have caused the issue in your other thread.
It may be worth trying the list (you may skip 5), and you may consider going straight to 6)).
The following is a general list of things you may try when the issue is not in a specific file (you may have tried/done some of them already); 1) and 2) are the easy ones for temporary strangenesses, and 3) and 4) are specifically aimed at possibly corrupt preferences); 5) is a list in itself, and 6) is the last resort.
If possible/applicable, you should save curent artwork first, of course.
1) Close down Illy and open again;
2) Restart the computer (you may do that up to 3 times);
3) Close down Illy and press Ctrl+Alt+Shift/Cmd+Option+Shift during startup (easy but irreversible);
4) Move the folder (follow the link with that name) with Illy closed (more tedious but also more thorough and reversible);
5) Look through and try out the relevant among the Other options (follow the link with that name, Item 7) is a list of usual suspects among other applications that may disturb and confuse Illy, Item 15) applies to CC, CS6, and maybe CS5);
Even more seriously, you may:
6) Uninstall, run the Cleaner Tool (if you have CS3/CS4/CS5/CS6/CC), and reinstall.
http://www.adobe.com/support/contact/cscleanertool.html

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