Glitches in recording, youtube and mp3 playback

Question

For two years now I've been struggling with this problem.  I record music with an RME Fireface to my Macbook Pro and very occasionally the recorded audio will have digital buzzes/glitches.  I've tried everything suggested on audio gear forums (larger buffer sizes, closing airport and open applications etc.).  It still does it, even on simple stereo recordings.  I've tried different DAW programmes and two different audio interfaces, updated/rolled back various drivers and firmware etc, etc.  The problem still persists.
Another seemingly related problem is that Youtube videos very often play back with split seconds of silence every now and then, even when the video is fully loaded.  And more recently playing mp3s in iTunes *occasionally* glitches.
From a process of elimination I can only assume the fault is in the Macbook's hard drive or RAM.  I took the Mac in a year ago because Techtool deluxe kept showing up a 'volume structure' error but they said don't worry about it.  However, now it seems like all this can't be coincidence!
Has anyone else had this problem?  It's very frustrating given how smooth the Apple experience is meant to be...

Answer 1

yeah you will have to cut it up, but you can run multiple playback instruments in the same patch so try layering them up that way.
another workaround would be to have long gaps between sections, put markers in at the beginning of each section and then just use skip to next marker instead of triggering a new instrument.
hope this helps