Good apps and games for the disabled?

My brother in law was born premature and as a result has a number of neurological and muscular problems. He has been wheelchair bound since he was very young, and mentally he will likely not develop past about a third grade intellect. He is currently 30, and his parents have gone to great lengths to take care of him as best they can. I've known him for about four years now, and he's got the personality of a guy that you can't help but like
My in laws live on the other side of the US as my wife and I do, but we're going to be flying out to visit them in a few weeks. I'm always seeing young kids at airports and the supermarket playing games on their parents' smartphones and tablets, and that got me to thinking that an iPad might make a great belated 30th birthday present for my brother in law. It's got an easy to understand interface, a touchscreen that's large enough for him to effectively interact with, and it could provide him with much more intellectual stimulation than watching The Price Is Right.
Before giving it to him, I'd really like to load it up with games that he will be able to play. I've never owned an iPhone or an iPad, though, so the only ones I'm familiar with are the super popular (Angry Birds and Cut the Rope) and what few games I've played around with on my Android powered phone.
Can anyone make some suggestions for me about apps that I could get for him? The more kid friendly, the better.  He does have limitations to motor control in his hands, so I think it'd be best if the app didn't require a high level of precision (for example, Slice It! probably wouldn't be too fun). I don't mind if it's not free- if I'm already spending a few hundred dollars on the hardware, $5 for software isn't a big deal
Thanks in advance!

Forgot to add this. You'll have to decide whether to get an iPad (new version, 3) or an iPad 2. Although a bit more costly, I would recommend the new iPad. It comes with a dictation app and when iOS 6 http://www.apple.com/ios/ios6/ is released in the fall, it will have Siri. With Siri, he can speak sites to go to in Safari, the browser. There is a free dictation app, Dragon Dictation, for the iPad 2. The 16GB model with wifi (no 3/4G) should meet his needs, unless he wants movies installed (then get the 32GB model).
What are all the differences between the iPad 3rd Gen and the iPad 2? Is the iPad 2 worth the cost savings?
http://everymac.com/systems/apple/ipad/ipad-faq/differences-between-ipad-3rd-gen -2012-ipad-2-2011.html
What are all the differences between the iPad 3rd Gen models? Which should I buy?
http://everymac.com/systems/apple/ipad/ipad-faq/differences-between-ipad-3rd-gen -early-2012-models.html
Should I Buy a New iPad? Or an iPad 2?
http://www.maclife.com/article/blogs/should_i_buy_new_ipad_or_ipad_2
iPad 3 vs iPad 2 vs iPad 1- Feature comparisons with iOS 5
http://ipadhelp.com/ipad-help/ipad-3-vs-ipad-2/
iPad Q&A
http://www.everymac.com/systems/apple/ipad/ipad-faq/differences-between-ipad-3rd -gen-early-2012-models.html
A Few Questions (and Answers) About the New iPad
http://pogue.blogs.nytimes.com/2012/03/15/a-few-questions-and-answers-about-the-   new-ipad/?ref=personaltechemail&nl=technology&emc=edit_ct_20120315
New iPad: A Polishing of the Old
http://www.nytimes.com/2012/03/15/technology/personaltech/the-new-ipad-is-much-t he-same-only-better.html?nl=technology&emc=edit_ct_20120315
iPad 1, 2 and New Specifications
http://www.everymac.com/systems/apple/ipad/index-ipad-specs.html
How much content will fit on my iPod or iPhone?
http://support.apple.com/kb/HT1867
If you think you may get an iPad 2:
Refurbished iPad Prices
http://store.apple.com/us/browse/home/specialdeals/ipad
New 16GB iPad 2 Prices
http://store.apple.com/us/browse/home/shop_ipad/family/ipad/select_ipad2
 Cheers, Tom

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