Greyed out menubar irems with CS5

A couple of days ago when I opened PS there was no splash screen and the menubar appeared immediately. Up until that time I had no problems. All of the items in the pulldowns are greyed out, and I am now unable to use PS at all. Drag and drop to the dock icon doesn't work, nor does opening directly from my applications folder. I have to force quit every time I try. I spent an hour on the phone with Adobe support and at that time I was told to uninstall and reinstall to CS5.1. In fact, they had me do that twice! Absolutely no help. I am running OS 10.6.7 on a 3.06 GHz Intel core duo with 4GB memory. I ran disk utility, DiskWarrior and Maintenance 3.8 and all said my machine is operating as it should. I'm beyond frustration now and ready to ter my hair out.
Any suggestions?
andy

Thanks for your reply! I am assuming I will have to spend a few hours removing and reinstalling OS10.6.7. Never having done that before, I would like to know if I should do a complete uninstall of PS first, back up everything to my external hard disk and then re-install the OS, then PS. I have tried trashing the prefs, but that does nothing. My concern is that whatever is causing my problem will remain on my backup before I transfer everything back to my internal drive, making the whole process pointless. I'll contact Applecare first before I do anything, though. Am I on the right track?

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