Guitar works on iMac, not MacBook

Very strange problem with GarageBand: Before the GarageBand '11 update, my electric guitar was working perfectly even when using the GB guitar effects. Since updating to '11 (and yes, I've installed the '11 software update) when monitoring the guitar through my speakers (or MacBook built-in speakers) it's ok for the first 5-10 seconds, but then there is a constant distortion noise and crackling and popping, as well as a severe delay (1-2 seconds) between the time I hit a note to the time I hear it. The latency is not there in the first 5-10 seconds, it only occurs when the distortion sound and crackling and pop sounds start. I wondered if my MacBook needed more than the 2GB of memory I have in it, so I installed a total of 4GB. Didn't help. Same problem. The problem is not my guitar or the interface cable (First Act) as I tried the identical setup on my iMac with 2GB memory, and it works flawlessly, even when using guitar effects. Is anyone else having this problem?
My MacBook:
Model Name: MacBook
Model Identifier: MacBook2,1
Processor Name: Intel Core 2 Duo
Processor Speed: 2 GHz
Number Of Processors: 1
Total Number Of Cores: 2
L2 Cache: 4 MB
Memory: 4 GB
Bus Speed: 667 MHz
Boot ROM Version: MB21.00A5.B07
SMC Version (system): 1.13f3

The problem with Windows Media files on Intel Macs at the moment is that there is no player available as a Universal binary. You can however install the Flip4Mac plugins although you will need to run both Quicktime and Safari under Rosetta… which you may not want to do. Anyway, here's what you do…
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Guitar works on iMac, not MacBook

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