Hard Disk filled with invisible volume

My HD,internal to my MacBookPro is named iPal
I use SuperDuper to create a bootable clone on a Western Digital External HD , brand name "My Book" which is the name I left for that drive
My MBP is 17 months old and the OEM Hitachi HD is 320 Gig,with approx 288 actually usable after formatting.
I have been pleased to note that I easily had half of my HD space left
Did my periodic back up: IPal to My Book approx 2 weeks ago.
At the time I did think the smart backup was taking far too long- seems like nearly 3 hours.
Early this past week I was horrified to be getting alerts that I was down to 15% of my HD space or roughly 45 GB remaining.
Could not find what was eating up space
I looked everywhere.. tossed ,disabled TechTool Pro "protection" which has a known issue of stealing multi Gig to create backup directories. Trashed those .Long story short. I had 45GB space left.
So,I purchased a new larger internal HD which I installed this weekend
Used SuperDuper to clone the new HD precisely to the internal.
new drive works wonderfully and everything is in place
But I was shocked to see that my new HD registers as having only 125 GB filled with my stuff.375 GB FREE!
the now externalized 320 GB,with replaced directory( Disk Warrior)), STILL shows only 45 GB free.
Same stuff..
Tonight I used Omni's Disc Sweeper and saw that
320 HD contains a Volume entitled "My Book" with 125 GB of stuff on iPal.
That number explains why the 320 HD is so full
but altho OmniSweeper sees it, I cannot find the volume nor its components..
The HD named iPal believes Western Digital My Book is internalized and part of it so the 320 HD shows those 125 GB as used.
Perhaps that explains the overly lengthy backup I noted two weeks ago.?
Have you ever had reports of something like this?Is this SuperDuper? Is it the Western Digital Drive?
I would like to know so I can protect from this.
When I reformat the now external 320 HD I will of course regain my space. But how did this happen?
Has anyone heard of something like this?

Yes, I have puzzled through precisely that scenario. I did set up the external target drive but it did not get a backup on 3/31 (when this happened). The backup was placed on my internal drive,hence eating so much space.
I am not sure if SuperDuper lost contact with the external HD but what I realized is:
Techtool Pro's protection control panel backs up the start up disk's directory apparently whenever there is a change such as an application installed, removed etc. So there are a bunch of these directories which in themselves gobble several gigabytes of disk space. The TechTool Pro apparently also backed up/copied the directory on backup drive and put those files into a folder , on my HD into a Volume (hidden) naming the folder the same name as the external Hard Drive's name.
I am not sure why but Super Duper thought the folder , created by TTP, named the same as the targer external HD,was where to put the backup. SuperDuper did what it was told to do, backed up into My Book except the My Book was the volume on my boot, internal HD
I used Filebuddy to make the hidden /Volume/My Book, make it visible and deleted it thus restoring 125 gig free space to the drive.
Apparently a volume is a volume to these back up programs (CCC or SuperDuper
I have turned off TTP, will reformat the back up drive with a new name,do a fresh complete backup and hope this does not happen again. Thank you

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