Has anybody had compatibility issues with Leopard and their scanners?

I recently installed Leopard on my G5. I'm still using Photoshop CS2 and so far no problems. Until today. I have a Epson Perfection 2450 scanner and today I went to scan some old photos. At first blush, no problem. I put in a second photo. Nothing. I get a 2 messages: The first says: "Make sure the scanner is on and properly set up to scan." Like, yeah. It was just working. The second message read Couldn't complete the import command because there is no scanner installed." I switched the USB port and it worked, once, and then same messages appeared when I tried to repeat. I went to Epson and downloaded a new driver to no avail. The same thing happened. I'm also having the same problem with my Nikon scanner. Photoshop or Leopard is creating problems for my scanners. I've updated all the necessary rivers. But nothing. I'm flummoxed.

I have used the same media type for the last year with no issue
Vendors change suppliers of discs; often one batch is not the same as another.
Media is THE most common cause of the error.
Solution is to change media, and don't but 16x media for a 8x or slower drive.
Another cause is out of date firmware, which can be updated easily in Windows.
Use DVRFlash to update firmware in OS X.

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