Has anyone else seen the "SharePoint is not supported with version 4.0.30319.18051" messages?

We are running SP 2010 service pack 2.
We are seeing the following messages on at least one of our farm machines. I was wondering whether others here have seen these messages and found a solution. The powershell ise was a running task, but not actually executing any code, etc.
When code was tried with it, the code appeared to be working as far as I could tell.
03/04/2014 15:25:11.28  powershell_ise.exe (0x162C)                     0x15EC  SharePoint Foundation          
Topology                        d04h    Monitorable     Microsoft SharePoint is not supported with version
4.0.30319.18051 of the Microsoft .Net Runtime.
03/04/2014 15:25:11.28  powershell_ise.exe (0x162C)                     0x15EC  SharePoint Foundation          
Topology                        888j    Medium          System.PlatformNotSupportedException:
Microsoft SharePoint is not supported with version 4.0.30319.18051 of the Microsoft .Net Runtime.     at Microsoft.SharePoint.Administration.SPConfigurationDatabase.get_Farm()     at Microsoft.SharePoint.Administration.SPConfigurationDatabase.SPFileSystemCacheWatcher.OnChanged(Object
source, FileSystemEventArgs e)

that appears to be doing the trick. I really appreciate your help.
It is weird - all that the kb recommends is changing the command line -version from "-version 2" to "-version 2.0".

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