Having difficulty opening some apps...

A number of apps are failing to open - each has a similar message -
"The application "Word" could not be launched because of a shared library error: "1<Microsoft Word><CarbonLib><CFMPriv_CarbonCore>"
I've recently added a LaCie external drive (Firewire), but can think of nothing else that might cause this.
I've tried to run the Disc Utility both from the HD and from the original Tiger cd - even tried to reinstall - to no avail. Anyone know if it's terminal?
eMac   Mac OS X (10.4.6)  

If Tiger 10.4.2 or later's Disk Utility> Repair Disk can't fix an invalid extent, I'd reach for the latest version of Disk Warrior. It's not cheap, but it's more cost-effective than backing up what you can to an external drive then doing a zero earse and install. Note: the Alsoft website says to allow several weeks for delivery; actual delivery in the US last time I ordered from them actually took about 3 days. Delivery to Oz will take longer but you should be able to find DW version 3.0.3 (don't use an earlier version with Tiger!) locally.
Another thought: when you ran Disk Utility, what did the SMART status at the bottom of the DU window report? Was it a message in red about drive failure? If the drive is physically bad, Disk Warrior would become a secondary option to getting a replacement hard drive, either internal or external.

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