HELP!  Click on desk top Icon and nothing...

Hi Everyone,
I'm new to the boards and am hoping I'm posting in the right area... When I click on the iTunes icon on my desktop nothing happens?? What do I do? I did try upgrading and it said it was successful, but still nothing?
Thank you for any help!
Jennifer in MI

Here's a few articles I dug up that may help you:
http://docs.info.apple.com/article.html?artnum=302775
http://docs.info.apple.com/article.html?artnum=302386
http://docs.info.apple.com/article.html?artnum=42963
Also take out any USB devices or USB hubs before launching iTunes. I ran into an issue a few months back (on my Windows machine) where iTunes wouldn't open if I had this certain usb gamepad plugged in. No fun!

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