Help! i can't save any changes in my preferences

when i change any the in my system preferences like trackpad or dock when i restart or switch on the system every thing is gone i have to repeat it agian what happend i don't know!!!!!!
please help

Boot from your install disc & run Repair Disk from the utility menu. To use the Install Mac OS X disc, insert the disc, and restart your computer while holding down the C key as it starts up.
Select your language.
Once on the desktop, select Utility in the menu bar.
Select Disk Utility.
Select the disk or volume in the list of disks and volumes, and then click First Aid.
Click Repair Disk.
Restart your computer when done.
Repair permissions after you reach the desktop-http://docs.info.apple.com/article.html?artnum=25751

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