Help please! Nothing is working...

I have a powerbook that is a little over a year old (and thus no longer under warrantly).
Last night, I attempted to open up limewire and then limewire wouldn't open, it just froze. My entire computer did, so I turned it off the manual way, and when I rebooted my computer, none of the programs (mail, safari, iphoto, etc...) would open.
Now this morning, it takes so long to open programs - that little rainbow circle keeps spinning. It's like the computer is trying to open the programs, but nothing works!
When I tried to open iphoto, I got a message that said there was no library. This isn't true, I had over 500 photos. Yikes!
PLEASE, if anyone can give me any advice, I will be eternally grateful! What should I do? What do you think happened?

Welcome to Apple Discussions, blindbunny.
I agree with Matt's suggestion that it may be a failing hard drive. There's enough in your description to suggest that it is a failing drive - though not 100% conclusive.
Other failing hard drive symptoms include additional unusual noises, startup problems and general sluggish performance (not just problems opening applications).
As already suggested, if you don't already have a backup of your essential data then this is most definitely the right time to get one (if it is still possible).
2.0GHz MacBook, 15" 1.25GHz/12" 1GHz PBs, 2xPPC Mac minis, 12" iBook G4,   Mac OS X (10.4.8)   Cube, 2xTAMs, iPod 4G & nano 2G, 1G & 2G iPs, AEBS, AX

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