How can I Isolate a specific structure from a series of photos in sequence. (like one ring from a tree cut in a hundred sections)

     I'm working with a series of images of the human body and I'm trying to isolate structures based on the image. Manually masking the structures frame by frame is the fall back plan but I'm searching for a more efficient and accurate way to separate out the data.
Imagine cutting a tree into a thousand slices and photographing each slice... the goal is to be able to isolate each individual ring separately throughout the series of sections.
The images are fully colored and quite large... something like 7860x4012 pix.

That's a tough call.  It all depends upon you original image.  The best bet is if your specimen samples have been stained to show the structure you want to isolate.  If so, you can look at the different color channels to see which channel brings out the detail that you want to isolate the best, then use that channel to make a selection.  Maybe make a duplicate of that channel and increase the contrast using curves or apply it to itself using multiply blend mode.

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