How can I protect files from being uploaded to the internet/web-based email or being written to a disc/flash drive?

I work for a company that want to update itself to this century.  I got all our PC upgraded to Windows 7 and networked into a homegroup.  We want to use a web-based appointment scheduler but this means giving our users web access.  The main
concern is our .mdb files.  We have anti-virus/anti-spyware to protect us from infiltration but we want to safeguard against personnel selling our client list; At least make it more difficult, just a precautionary measure.  Do I need additional software
or is it something that I can do in Windows setting?  Or do I need a file encryption service that works in conjunction with Windows Access?  Sorry for my ignorance and thanks in advance.

There is technology known as RMS which you could set series of policies like only members in the company could access certain documents and if someone copy them and attempt to run them in another PC or outside company, it won't work. Take a look at:
http://blogs.technet.com/b/rms/archive/2013/08/29/the-new-microsoft-rms-is-live-in-preview.aspx
https://technet.microsoft.com/en-us/library/dd277361.aspx

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