How do I close and save an InDesign file. I lose all changes.

I download an ID rext file, make changes, save. How do I get it uploaded so that when I download to work again my changes are not lost? Should I be keeping the file on my desktop, working, saving, and uploading to Cloud when closed? I am so confused.

Thank you! I get it now. I have ID sitting here in my computer and can work anytime and also send files to storage. Thank you!
Sarah

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