How do I get my Synth Hardware to play through my Mac Soundsystem?

I want to use my drum machines and hardware synths through my Mac just like all the plug-in/Virtual Synths... But I don't know how to accomplish this...
I have your standard 1/4" output plugs on my Synth Gear (Hardware) and want to get it to play through core audio like my Virtual Synths do. Also, I'd like to control and record them through my DAW.
What is the best way to accomplish this "feat"?
Thanks in advance!

Question:
I take it you have a set of decent external speakers plugged into the Mac Pro, right?
My question is... isn't the Alesis MultiMix6 a full fledged audio interface?
If you're using Logic Nine you set the Preferences/Audio/Input to the Alesis as it should be your primary recording interface. The output can be set to the Mac's built-in audio. Then the audio outs of the drum machine, (as well as any other audio outs) are plugged into the Alesis.
But here's the thing... why do you spend money on a mixer/audio interface and then try and use the cheap built-in audio of the Mac for anything? The Alesis is designed to be the center hub of the studio.
Your speakers should be plugged into the audio interface so that when using Logic the Alesis is both the Main input and Main output, your audio will sound better. If you need to monitor the Macs output maybe you can set it up in the Mac's audio setup. (monitor the mac through the USB connection.)
pancenter-

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