How do I sync with a new computer without losing everything?

I no longer have access to the computer I originally synced my iPhone with.  I want to sync it with a new computer and back everything up without losing anything.  How do I do that?  Please help!

Using the information below you can transfer content to your new computer.  Thiis will at least update the content to have what is on your phone but you will still be syncing with a new iTunes library.  It will replace your content but hopefully you can make the replaced content match your existing content.
Make a backup of your computer always.  This is the digital age and it is all too easy to lose music and photos in an instant.
Some of the information below has subsequently appeared in a document by turingtest2: Recovering your iTunes library from your iPod or iOS device - https://discussions.apple.com/docs/DOC-3991
Your i-device was not designed for unique storage of your media. It is not a backup device and media transfer was planned with you maintaining a master copy of your media on a computer which is itself properly backed up against loss. Syncing is one way, computer to device, updating the device content to the content on the computer, not updating or restoring content on a computer. The exception is iTunes Store purchases which can be transferred to a computer.
iTunes Store: Transferring purchases from your iOS device or iPod to a computer - http://support.apple.com/kb/HT1848 - only purchases from iTunes Store
For transferring other items from an i-device to a computer you will have to use third party commercial software. Examples (check the web for others; this is not an exhaustive listing, nor do I have any idea if they are any good):
- Expod (free) - http://www.headlightsoft.com/expod/ - Mac, universal for 104.+ (newer machines try de-Tune)
- deTune (free) - http://www.headlightsoft.com/detune/ - Mac, 10.5+
- Senuti - http://www.fadingred.com/senuti/
- Phoneview - http://www.ecamm.com/mac/phoneview/
- MusicRescue - http://www.kennettnet.co.uk/products/musicrescue/
- Sharepod (free) - http://download.cnet.com/SharePod/3000-2141_4-10794489.html?tag=mncol;2 - Windows
- Snowfox/iMedia - http://www.mac-videoconverter.com/imedia-transfer-mac.html - Mac & PC
- iexplorer (free) - http://www.macroplant.com/iexplorer/ - Mac&PC
- Yamipod (free) - http://www.yamipod.com/main/modules/downloads/ - PC, Linux, Mac [Still updated for use on newer devices? No edits to site since 2010.]
- 2010 Post by Zevoneer: iPod media recovery options - https://discussions.apple.com/message/11624224 - this is an older post and many of the links are also for old posts, so bear this in mind when reading them.
Syncing to a "New" Computer or replacing a "crashed" Hard Drive - https://discussions.apple.com/docs/DOC-3141 - dates from 2008 and some outdated information now.
Copying Content from your iPod to your Computer - The Definitive Guide - http://www.ilounge.com/index.php/articles/comments/copying-music-from-ipod-to-co mputer/ - Information about use in disk mode pertains only to older model iPods.
Get Your Music Off of Your iPod - http://howto.wired.com/wiki/Get_Your_Music_Off_of_Your_iPod - I am not sure but this may only work with some models and not newer Touch, iPhone, or iPad.
Additional information here https://discussions.apple.com/message/18324797

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