How do you updated CS5 Extended when you keep getting a message to close the program but it is close

How do you updated CS5 extended when you keep getting a message to close the program but the program is already closed?  I have tried to do the update when I first turn the computer on, go directly to Photoshop, go to update and click on that, get new screen, close Photoshop, and I still get a message to close the already closed program.  I believe I have to open Photoshop to get to the update area, so I don't know how to get around this issue.  I hope someone can help me.
(I use win8, 64 bit)
Thank you in advance to all who answer my request for help.
Ann

Thank you for answering.  However, when I opened the Task Manager and looked at all the processes that were running, the only things running were the Task Manager and the browser.  None of the Photoshop programs were running.  So, do you have any other suggestions?

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