How to change which programs run at start up

Hello,
I am just trying to speed up and clean up my machine.  I would like to know how to control which programs run at start up.  Also any other suggestions on how to keep everything running smoothly and effifiently.  General maintenance type stuff.
Thanks, Jason

How to maintain a Mac
1. Make redundant backups, keeping at least one off site at all times. One backup is not enough. Don’t back up your backups; make them independent of each other. Don’t rely completely on any single backup method, such as Time Machine.
2. Keep your software up to date. In the Software Update preference pane, you can configure automatic notifications of updates to OS X and other Mac App Store products. Some third-party applications from other sources have a similar feature, if you don’t mind letting them phone home. Otherwise you have to check yourself on a regular basis. This is especially important for complex software that modifies the operating system, such as device drivers. Before installing any Apple update, you must check that all such modifications that you use are compatible.
3. Don't install crapware, such as “themes,” "haxies," “add-ons,” “toolbars,” “enhancers," “optimizers,” “accelerators,” “extenders,” “cleaners,” “defragmenters,” “firewalls,” "barriers," “guardians,” “defenders,” “protectors,” most “plugins,” commercial "virus scanners,” or "utilities." With very few exceptions, this kind of material is useless, or worse than useless.
The more actively promoted the product, the more likely it is to be garbage. The most extreme example is the “MacKeeper” scam.
The only software you should install is that which directly enables you to do the things you use a computer for — such as creating, communicating, and playing — and does not modify the way other software works. Never install any third-party software unless you know how to uninstall it.
The free anti-malware application ClamXav is not crap, and although it’s not routinely needed, it may be useful in some environments, such as a mixed Mac-Windows enterprise network.
4. Beware of trojans. A trojan is malicious software (“malware”) that the user is duped into installing voluntarily. Such attacks were rare on the Mac platform until recently, but are now increasingly common, and increasingly dangerous.
There is some built-in protection against downloading malware, but you can’t rely on it — the attackers are always at least one day ahead of the defense. You can’t rely on third-party protection either. What you can rely on is common-sense awareness — not paranoia, which only makes you more vulnerable.
Never install software from an untrustworthy or unknown source. If in doubt, do some research. Any website that prompts you to install a “codec” or “plugin” that comes from the same site, or an unknown site, is untrustworthy. Software with a corporate brand, such as Adobe Flash Player, must be acquired directly from the developer. No intermediary is acceptable, and don’t trust links unless you know how to parse them. Any file that is automatically downloaded from a web page without your having requested it should go straight into the Trash. A website that claims you have a “virus,” or that anything else is wrong with your computer, is rogue.
Because of recurring security issues in Java, it’s best to disable it in your web browsers, if it’s installed. Few websites have Java content nowadays, so you won’t be missing much. This action is mandatory if you’re running any version of OS X older than 10.6.8 with the latest Java update. Note: Java has nothing to do with JavaScript, despite the similar names. Don't install Java unless you're sure you need it. Most users don't.
5. Relax, don’t do it. Besides the above, no routine maintenance is necessary or beneficial for the vast majority of users; specifically not “cleaning caches,” “zapping the PRAM,” “rebuilding the directory,” “running periodic scripts,” “deleting log files,” “scanning for viruses,” or “repairing permissions.” Such measures are for solving problems as they arise, not for maintenance.
The very height of futility is running an expensive third-party application called “Disk Warrior” when nothing is wrong, or even when something is wrong and you have backups, which you must have. Disk Warrior is a data-salvage tool, not a maintenance tool, and you will never need it if your backups are adequate. Don’t waste money on it or anything like it.

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