How to comment on large pdf without slowing down?

I am using the commenting and annotations function to highlight and draw textboxes on a large pdf.  I have found as I go through the document the more of these I do the slower the function becomes (now taking appox 9-10 for each function, ie, to highlight, then to draw box, then to write in box) and am only about a quarter of the way through.  Is there a better/quicker way of markup up documents?

Thank you for your response.
I should have explained better and we have continued to work on this.  The initial work was done on a machine without a lot of memory. After moving to a machine with more memory, Acrobat is able to handle some files.  But on one with 7700 pages it get a message "And error was encounted while processing images".  And when that dialog is closed another comes up saying "Insufficeint data for an image" and then the hourglass stays up. It seems like it runs out of memory.
In terms of what errors are in the file, what I do know is that Acrobat will put up the dialog saying "An error exists on this page. ... Contact the person who created the PDF document to correct the problem".
I have tried the Preflight. I have tried the compliance with the Acrobat 5 and it doesn't find any errors. Some errors are reported on PDF/  Is there a way to find out what causes the initial reported error.  There are a lot of individual repairs that can be made, but this seems to be too much trial and error.  That is why I used the Save As Optimized, which does seem to work on smaller files, but does fail on the larger ones.
Thank you for any suggestions,
Jeff

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