How to disable spam/virus ?

We are running 10.4.11, disabled all options in Filters tab and mail gets stuck in the queue. I checked main.cf and it looks fine. How to disable spam/virus permanently and let mail thru ?
Before disabling filter, postconf -n :
alias_maps = hash:/etc/aliases
command_directory = /usr/sbin
config_directory = /etc/postfix
content_filter = smtp-amavis:[127.0.0.1]:10024
daemon_directory = /usr/libexec/postfix
debugpeerlevel = 2
enableserveroptions = yes
html_directory = no
inet_interfaces = all
mail_owner = postfix
mailboxsizelimit = 0
mailbox_transport = cyrus
mailq_path = /usr/bin/mailq
manpage_directory = /usr/share/man
mapsrbldomains =
messagesizelimit = 10485760
mydestination = $myhostname,localhost.$mydomain,localhost,mydomainslist
mydomain = domain.net
mydomain_fallback = localhost
myhostname = domain.net
mynetworks = 127.0.0.1/32
mynetworks_style = host
newaliases_path = /usr/bin/newaliases
ownerrequestspecial = no
queue_directory = /private/var/spool/postfix
readme_directory = /usr/share/doc/postfix
recipient_delimiter = +
sample_directory = /usr/share/doc/postfix/examples
sendmail_path = /usr/sbin/sendmail
setgid_group = postdrop
smtpdpw_server_securityoptions = plain,login,cram-md5
smtpdrecipientrestrictions = permitsasl_authenticated,permit_mynetworks,reject_unauthdestination,permit
smtpdsasl_authenable = yes
smtpdtls_keyfile =
smtpduse_pwserver = yes
unknownlocal_recipient_rejectcode = 550
virtualaliasmaps = hash:/etc/postfix/virtual
virtualmailboxdomains = hash:/etc/postfix/virtual_domains
virtual_transport = lmtp:unix:/var/imap/socket/lmtp

I just want to add that i followed pterobyte's instructions from http://discussions.apple.com/thread.jspa?threadID=2402121&tstart=0 and updated ClamAV. It seemed to work fine for a day and all of a sudden mails were getting queued.

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relayhost = 192.168.0.000.
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Please respond: [email protected]

Hi,
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[http://kb.mozillazine.org/About:config_entries about:config Entries]

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========
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