How to fix a problem blinking application? but finder is'nt crashing

just like me use applications suddenly blinking in and out every application ,example : me click photoshop icon after that blinking in and out and i try click safari, it blinking of gray and me clik 2 x again
.. after this i restart 3 x my imac just normal
anyone can fix it?i really confuse

Could be many things, we should start with this...
"Try Disk Utility
1. Insert the Mac OS X Install disc, then restart the computer while holding the C key.
2. When your computer finishes starting up from the disc, choose Disk Utility from the Installer menu at top of the screen. (In Mac OS X 10.4 or later, you must select your language first.)
*Important: Do not click Continue in the first screen of the Installer. If you do, you must restart from the disc again to access Disk Utility.*
3. Click the First Aid tab.
4. Select your Mac OS X volume.
5. Click Repair Disk, (not Repair Permissions). Disk Utility checks and repairs the disk."
http://docs.info.apple.com/article.html?artnum=106214
Then try a Safe Boot, (holding Shift key down at bootup), run Disk Utility in Applications>Utilities, then highlight your drive, click on Repair Permissions, reboot when it completes.
(Safe boot may stay on the gray radian for a long time, let it go, it's trying to repair the Hard Drive & clear caches.)
If perchance you can't find your install Disc, at least try it from the Safe Boot part onward.
Also...
Boot off your Install Disk while holding down the *d key*, (not c key), then run the extended Apple Hardware Test. Some disks require you to use the Option key at bootup to select AHT. AHT may be on a second Disc if there was one.

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