HT1926 itunes will not run and indicates apple application support is needed?

After installing itunes on a pc running vista, when I try to run it I get a message sayinjg "Apple application support is needed to run itunes.  Uninstall itunes and reinstall.  error 2"
Apple application support is installed
itunes was installed by running setup as an administrator.
itunes has been uninstalled and re-installed to no avail.
please advise! 

See Troubleshooting issues with iTunes for Windows updates.
tt2

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