Hyperlinks in mail not working

Question

Bit of an odd problem. If I click on a hyperlink in mail with Safari closed it does nothing. Again if I right and select the open option from there it does nothing. If Safari is open, irrespective of what page it's on, Safari opens in front of mail, but doesn't take me to the page it just stays on the page it opened at.. It seems to stem from my installing Chrome, which I have now uninstalled using 'CLEAN MY MAC'. When I go into Safari preferences I now expect to only see one default web browser, but the Chrome option still appears. I have tried resetting Safari. Can I delete and re install Safari or is there a plist or something that is corrupt.
Ken

Answer 1

"CleanMyMac" is a scam and a common cause of instability and poor performance. The developer's instructions don't completely remove it. Follow those instructions, then do as below.
Back up all data before proceeding.
Triple-click anywhere in the line below on this page to select it:
/Library/LaunchDaemons/com.macpaw.CleanMyMac2.Agent.plist
Right-click or control-click the highlighted line and select
          Services ▹ Reveal in Finder (or just Reveal)
from the contextual menu.* A folder should open with an item selected. Move the selected item to the Trash. You may be prompted for your administrator login password. Repeat with this line:
/Library/PrivilegedHelperTools/com.macpaw.CleanMyMac2.Agent
Restart the computer and empty the Trash. Never again install "CleanMyMac" or anything like it.
*If you don't see the contextual menu item, copy the selected text to the Clipboard by pressing the key combination command-C. In the Finder, select
          Go ▹ Go to Folder...
from the menu bar and paste into the box that opens by pressing command-V. You won't see what you pasted because a line break is included. Press return.
Then reinstall the OS.* You don't need to erase the startup volume, and you won't need the backup unless something goes wrong. If the system was upgraded from an older version of OS X, you may need the Apple ID and password you used.
If you use FileVault 2, then before running the Installer you must launch Disk Utility and select the icon of the FileVault startup volume ("Macintosh HD," unless you gave it a different name.) It will be nested below another icon with the same name. Click the Unlock button in the toolbar and enter your login password when prompted. Then quit Disk Utility to be returned to the main Recovery screen.
If you installed the Java runtime distributed by Apple and still need it, you'll have to reinstall it. The same goes for Xcode. All other data will be preserved.
*The linked support article refers to OS X 10.9 ("Mavericks"), but the procedure is the same for OS X 10.7 ("Lion") and later.