I am getting continuous "no route to host" errors

I am getting hundreds of these messages a day and my connections are very slow.
1/28/15 10:41:33.971 AM nsurlsessiond[179]: tcp_connection_destination_prepare_complete 3 connectx to 17.253.16.221:80@0 failed: No route to host
also at 69.164.12.53 and 8.27.250.126 and others.
Chrome is slow loading Google Mail and pages.
Just updated to 10.10.2, which didn't help.
  Model Name: Mac mini
  Model Identifier: Macmini6,2
  Processor Name: Intel Core i7
  Processor Speed: 2.3 GHz
  Number of Processors: 1
  Total Number of Cores: 4
  L2 Cache (per Core): 256 KB
  L3 Cache: 6 MB
  Memory: 16 GB
  Boot ROM Version: MM61.0106.B03
Ethernet:
  Type: Ethernet
  BSD Device Name: en0
  Hardware (MAC) Address: a8:20:66:12:59:5a
  IPv4:
  Configuration Method: DHCP
  IPv6:
  Configuration Method: Automatic
  DNS:
  Server Addresses: 2001:4860:4860::8888, 2001:4860:4860::8844
  Proxies:
  Exceptions List: *.local, 169.254/16
  FTP Passive Mode: Yes

Are there any other devices on your network, and if so, are they having Internet problems? If you haven't already done so, please restart the router (and the broadband adapter, if they're separate.)

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