I am having trouble with syncing my iPhone 5 to my iTunes on my macbook

I have been trying to sync my iphone 5 with my macbook but itunes keeps saying 'error (-54)'. I downloaded new albums and they will not sync onto my iphone, and this has never been a problem in the past. Also, on my itunes, when i click on 'Iphone' it shows some of the song titles faded out with a dotted circle beside them, indicating that they cannot be played. I have tried restarting my mac but it has not worked. Could anyone help me?

Hello, katieokane1. 
Thank you for visiting Apple Support Communities.
This sounds like a possible permission issue with the iTunes Media Folder.  Follow the steps in the article below to make sure the permissions are set to read and write.  You can also navigate to ~/music/iTunes/iTunes Media and get info on to make sure permissions are set to read and write.
Troubleshooting permissions issues in Mac OS X
http://support.apple.com/kb/ht2963
iTunes: Missing folder or incorrect permissions may prevent authorization
http://support.apple.com/kb/ts1277
Cheers,
Jason H.

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