I can not open photoshop CS5! Please help me!

I have had CS5 on my mac for a while now... no problems.  All of a sudden photoshop will not open.  Icon flashes once... nothing!!!  Bridge I can access. I have uninstalled and reinstalled 2x's... still nothing.  What can I do?

Trash the prefs in the preferences folder.
Important Directories
Mylenium

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