I can not open up itunes using the desktop icon

I have installed, uninstalled and reinstalled the latest version if itunes.  I cannot get itunes to open up by clicking on the desktop icon.  I keep getting the message"Do you want to allow this program to make changes?"  The program is Apple Inc.  I click on yes but nothing happens.  I have set itunes to run as the adminstrator. Can anyone help me?

Odd that it is launching fine once after the repair.
We'd better check to see if it's a compatibility mode issue.
Try the following document, only be sure that none of the boxes in the compatibility mode tab are checked (not just the compatibility mode box itself):
iTunes for Windows: How to turn off Compatibility Mode

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