I can not safe changes of preferences in Mail or Adressbook

Hello,
I am using Lion on a MB pro. All Software is up to date. There are two users installed - both with admin rights.
The one I am using everything is fine. Today my wife changed on her account some preferences in Mail, but she
wasn't able to safe those changes. There appeared an error messages that maybe the right at library/prefrendes are
not ok. When we try to change preferences in other programs it is equal. Never before we had a problem like this!
So first I looked up the rights via finder. No visible problem. Nevertheless I repaired all the rights after restart from the recovery volume,
even the rights of the user folders. BUT PROBLEM STILL REMAINS.
Is there anybody who has an idea or must I create a new user?
Thank you for your help.
M

Do you have Adblock Plus installed? If you do, disable on the page where you normally see your stock info. I've uploaded an image of what happens on another site where ABP is enabled. The Global News image disappears with ABP enabled even though it's not an ad.
If that doesn't work, try running Firefox in [[Safe Mode]]. If it works correctly in that configuration, then one of your add-ons is the culprit.

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