I can't open PDF's but I was able to do it last week.

I can't open PDF's but I was able to do it last week.  Does anyone have a resolution?

OK,,,I'm back,  the version of reader is adobe reader XI.  The OS is WINDOWS 7. The PDF is off the desktop and emails. I am opening them up by double clicking and when I try I get the error message the operating system is not presently configured to run this application.

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