I can't open up iTunes

I had bought an iPod nano and then I exchanged it for the exact same iPod just a different color. But when I plug in the cord, shouldn't the Setup assistence pop up? And I had downloaded the brand new version of iTunes (It wasn't an update)and when I try to open it up, a pop-up comes on and saids:
The folder "iTunes" cannot be found or created, and is required. The default location for this folder is the "My Music" folder.
What is wrong then?
Windows 2000

Hey jcbui,
The tips in this article: http://docs.info.apple.com/article.html?artnum=302398 should help you resolve the issue.
Jason

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