I get a gray screen with the apple logo at start up and the trackpad doesn't work

My MacBook Pro has run fine until yesterday. It froze and wouldn't receive commands from the trackpad. I was still able to move the cursor but clicking or tapping the screen did nothing. I tried restarting but got the gray screen with the Apple logo and the spinning wheel. To get pass this I have tried resetting the NVRAM/PRAM and performing the safe boot. I also tried using the Disk Utility at start up but since I can't use the trackpad it was unsuccesful. I got pass the gray screen once performing the safe boot and restarted and everything run fine (including the trackpad) for about 20 minutes before freezing again. Now I'm back at the gray screen again and can't seem to get pass it again.
Any advice what should I do next?

I would back up the files and start looking at the HDD.  Open DISK UTILITY>FIRSTAID.
Ciao.

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    If the startup process hangs again, the problem is likely caused by a third-party system modification that you installed. Post for further instructions.
    Step 8
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