I have an issue that I cannot open Firefox, and I get the message "Firefox is already running..." and it says I need to close it or restart my computer.

There is a page on the support site that attempts to adress the issue...but it never says how to fix it. https://support.mozilla.com/en-US/kb/Firefox+is+already+running+but+is+not+responding
Apparently there is a problem with the "profile", and on this support page, it has a link about working with the profile...if you go to that page, is tells you where the profile is, and the many things it does...but it does NOT say actually how to fix this problem. It tells you to go the the Help tab at the top of the browser, then select "Troubleshooting", and then under Profile, select "Open Containing folder"...which brings up the folder with all the files...but from there...it doesn't say what to do. I also have gone to the Start tab at the bottom of Windows (Windows XP--I've got Firefox 3.6.9) then Run and opened the profile box...but there are no instructions on what to do to fix the problem. I can open Firefox only by going to Crtl-Alt Delete and opening the process tab and ending the Firefox process...but this is not a fix. Help! thanks...

You need "sysinternal's process explorer", it is free and can replace the Microsoft process explorer, that you get by "CTRL+ALT+DELETE". Either program will allow you to kill the instances of FF that didn't die as they should have, when you closed them. Sysinternal is easier to use, it is a graphic display with many options. Do not push "CTRL+ALT+DELETE" twice unless you want to reboot, that is its default behaviour under Microsoft.

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