I have messed up the settings on my Mighty Mouse and don't know where they should be.  I cannot open a document by double-clicking anymore.  I don't know what setting adjusts that.

I need help with my Mighty Mouse settings.  Don't understand the settings.  I can no longer open a document by double-clicking.  I think I changed my setting someway when I was trying to correct or find my up and down scrolling.   Please help. 

I think you need to un-pair your mouse.   Leave it a few minutes than re-pair it as if you were starting from scratch and using the following details.   Item 1 will probably meet your needs.
Troubleshooting wireless mouse and keyboard issues

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