I have tried all the fixes but thunderbird freezes on start up

I think i received an email last week with no subject, since then thunderbird freezes on start up. I have tried safe mode, removed global and removed all .msf's. My thunderbird runs mutliple acc's, pop and imap.
Many thanks for any help.
P.s. If I un-install thunderbird and then re-install will I loose all my accounts ?

Try to start *Windows* in safe mode with networking enabled.
- Win8 http://windows.microsoft.com/en-US/windows-8/windows-startup-settings-including-safe-mode
- Win7 http://windows.microsoft.com/en-US/windows7/Start-your-computer-in-safe-mode
- XP http://www.microsoft.com/resources/documentation/windows/xp/all/proddocs/en-us/boot_failsafe.mspx
Still in Windows safe mode, start Thunderbird in safe mode.
- https://support.mozilla.org/en-US/kb/safe-mode
Does the problem go away?

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