I´M using Lion 10.7.3 and I can´t running system preferences

I´M using Lion 10.7.3 and I can´t running system preferences. I can´t change or check anything because the screen is "frozen" and the time of response is over and I must to force quit of the app.

Do a safe boot. Then remove the system preference plist
www.apple.com/support/lion - link to Lion Community
If you want MacBook Pro Community
www.apple.com/support/macbookpro

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