I/O problems after installing latest 10.5.2 update

Since the last 10.5.2 update, when I close the lid on my 15 inch MacBook Pro, it goes into sleep mode, even though I have an external keyboard, mouse and LCD monitored plugged in. Before the latest update, I used to be able to close the lid and work using external monitor, keyboard and mouse.
Help appreciated

I closed Acrobat, then closed other apps, then re-opened the PDF in Acrobat. Seems to be ok now.

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