Illustrator CS6 Constant Error Messages

Hi guys,
I purchased CS6 about 5 months ago now. And for the last 3 months I have been getting constant Error 16 messages when trying to start up the program. It has become a vicious cycle of uninstalling, deleting all my adobe products, then deleting all of my adobe file folders under the C: drive, App data folders, and my User folders, then having to reinstall everything. I have been doing this consistently for 3 months and it's getting to the point of seriously disabling my workflow and costing my business way to much time. I even now today had a new problem arise. When I reinstall Illustrator and enter my serial number during the installation process it accepts it and installs fine. But when I open up Illustrator it prompts me that my trial has expired and to enter in a serial number. So I enter in my serial number again and then it works for a bit. If I close the program and reopen it literally 5 minutes later it Error 16 again.
I'm running a Dell Inspiron 15R Intel i-7 processor, 8GB RAM and Windows 8. Does anybody have any ideas on why Illustrator continues to crash and/or Error 16 almost every other day/week?
Thanks.
Here is the Error:16 message
Besides the Error 16 message I am also still having trouble with the Activation and serial number recognition of Illustrator. I went to open Illustrator up today and I got this message:
It says "Activation Failed". The message is saying Product Activation is required to use this product. You must have a working internet connection to activate this product. I have full strength internet connection and I have already activated Illustrator when I did a fresh install on 12/12/13. First is was the Error:16, then it was the trial problem, and now This. What is going on?
My serial number is clearly validated and activated but the very next day I try to open Illustrator I get the message in the screenshot above. How can I fix this? Thanks.

Jeff A Wright,
Thank you for your support on this. However, I am running into some problems for completing the steps listed on the help page you listed. In the SLStore the deselection of "Read-Only" is not being applied. I deselect that attribute and click Apply and then Ok. If I right click again on the folder the "Read-Only" attribute is still checked.
Also for step 3 Set Permissions I cannot change any of the permissions for the SLStore even though I am logged in as the Administrator. The PCD folder does not have an Owner tab and I cannot change the permissions for this folder either.
What can I do to fix the file permissions if I am having the problems above?
Thank you.

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