IMac Ram is constantly being eaten up. Advice...

Hi,
I have a late 2012 iMac with 8gb ram,  1tb HD.    Recently installed Memory Clean and I find there is barely any ram memory available and is often in the 15-100MB range and am connately having to clean it to get back about 2 gb of ram.  Seems odd that the Mac would use 6 GB constantly.  Looked into Activity Monitor but don't know much about what I am looking at.  Here is my report from EtreCheck:
Anyone have expertise or advice on how to fix the problems below?  Thanks so much.
Before:
After
Problem description:
8 gig ram but always very low availability…using Memory Clean but never gets more than 2.5 gigs available…and quickly goes down to 20 megs avail….
EtreCheck version: 2.0.11 (98)
Report generated November 16, 2014 at 8:03:41 PM EST
Hardware Information: ℹ️
  iMac (21.5-inch, Late 2012) (Verified)
  iMac - model: iMac13,1
  1 2.7 GHz Intel Core i5 CPU: 4-core
  8 GB RAM Upgradeable
  BANK 0/DIMM0
  4 GB DDR3 1600 MHz ok
  BANK 1/DIMM0
  4 GB DDR3 1600 MHz ok
  Bluetooth: Good - Handoff/Airdrop2 supported
  Wireless:  en1: 802.11 a/b/g/n
Video Information: ℹ️
  NVIDIA GeForce GT 640M - VRAM: 512 MB
  iMac 1920 x 1080
System Software: ℹ️
  OS X 10.10 (14A389) - Uptime: 3 days 5:9:21
Disk Information: ℹ️
  APPLE HDD ST1000LM024 disk0 : (1 TB)
  S.M.A.R.T. Status: Verified
  EFI (disk0s1) <not mounted> : 210 MB
  Macintosh HD (disk0s2) /  [Startup]: 999.35 GB (501.67 GB free)
  Recovery HD (disk0s3) <not mounted>  [Recovery]: 650 MB
USB Information: ℹ️
  Western Digital Elements 10A8 500.07 GB
  S.M.A.R.T. Status: Verified
  My Passport (disk2s1) /Volumes/My Passport : 500.07 GB (366.05 GB free)
  Western Digital My Passport 071D 1 TB
  S.M.A.R.T. Status: Verified
  EFI (disk1s1) <not mounted> : 210 MB
  Time Machine 1TB (disk1s2) /Volumes/Time Machine 1TB : 999.83 GB (291.68 GB free)
  Apple Inc. FaceTime HD Camera (Built-in)
  Apple Inc. BRCM20702 Hub
  Apple Inc. Bluetooth USB Host Controller
Thunderbolt Information: ℹ️
  Apple Inc. thunderbolt_bus
Gatekeeper: ℹ️
  Mac App Store and identified developers
Kernel Extensions: ℹ️
  /Applications/Toast 8 Titanium/Toast Titanium.app
  [not loaded] com.roxio.BluRaySupport (1.1.3) Support
  [not loaded] com.roxio.TDIXController (1.7) Support
  /System/Library/Extensions
  [not loaded] com.leapfrog.codeless.kext (2) Support
  [not loaded] com.leapfrog.driver.LfConnectDriver (1.9.8 - SDK 10.7) Support
  [not loaded] com.wdc.driver.IOFireWireWDHID (1.1.2) Support
Startup Items: ℹ️
  HP IO: Path: /Library/StartupItems/HP IO
  WDBMService: Path: /Library/StartupItems/WDBMService
  Startup items are obsolete and will not work in future versions of OS X
Problem System Launch Agents: ℹ️
  [failed] com.apple.cmfsyncagent.plist
  [failed] com.apple.coreservices.appleid.authentication.plist
  [failed] com.apple.EscrowSecurityAlert.plist
  [failed] com.apple.gamed.plist
  [failed] com.apple.printtool.agent.plist
  [failed] com.apple.recentsd.plist
  [failed] com.apple.SafariNotificationAgent.plist
  [failed] com.apple.sbd.plist
  [failed] com.apple.scopedbookmarkagent.xpc.plist
  [failed] com.apple.security.cloudkeychainproxy.plist
  [failed] com.apple.spindump_agent.plist
  [failed] com.apple.telephonyutilities.callservicesd.plist
  [failed] com.apple.xpc.loginitemregisterd.plist
Problem System Launch Daemons: ℹ️
  [failed] com.apple.AssetCacheLocatorService.plist
  [failed] com.apple.coresymbolicationd.plist
  [failed] com.apple.ctkd.plist
  [failed] com.apple.findmymac.plist
  [failed] com.apple.icloud.findmydeviced.plist
  [failed] com.apple.ifdreader.plist
  [failed] com.apple.Kerberos.digest-service.plist
  [failed] com.apple.nehelper.plist
  [failed] com.apple.periodic-daily.plist
  [failed] com.apple.sandboxd.plist
  [failed] com.apple.wdhelper.plist
  [failed] com.apple.xpc.smd.plist
  [failed] org.cups.cupsd.plist
Launch Agents: ℹ️
  [invalid?] com.maintain.LogOut.plist Support
  [invalid?] com.maintain.PurgeInactiveMemory.plist Support
  [invalid?] com.maintain.Restart.plist Support
  [invalid?] com.maintain.ShutDown.plist Support
  [invalid?] com.maintain.Sleep.plist Support
  [running] com.maintain.SystemEvents.plist Support
  [loaded] com.oracle.java.Java-Updater.plist Support
Launch Daemons: ℹ️
  [loaded] com.adobe.fpsaud.plist Support
  [loaded] com.leapfrog.connect.authdaemon.plist Support
  [invalid?] com.lsreset.plist Support
  [invalid?] com.maintain.AutoLoginUserScreenLocked.plist Support
  [invalid?] com.maintain.CocktailScheduler.plist Support
  [invalid?] com.maintain.HideSpotlightMenuBarIcon.plist Support
  [loaded] com.oracle.java.Helper-Tool.plist Support
  [loaded] com.oracle.java.JavaUpdateHelper.plist Support
User Launch Agents: ℹ️
  [loaded] com.google.keystone.agent.plist Support
User Login Items: ℹ️
  Music Manager UNKNOWN (missing value)
  Dropbox Application (/Applications/Dropbox.app)
Internet Plug-ins: ℹ️
  Flip4Mac WMV Plugin: Version: 2.4.1.4 Support
  AmazonMP3DownloaderPlugin101736: Version: AmazonMP3DownloaderPlugin 1.0.17 - SDK 10.4 Support
  FlashPlayer-10.6: Version: 15.0.0.223 - SDK 10.6 Support
  Flash Player: Version: 15.0.0.223 - SDK 10.6 Support
  Default Browser: Version: 600 - SDK 10.10
  JavaAppletPlugin: Version: Java 7 Update 71 Check version
  QuickTime Plugin: Version: 7.7.3
  AmazonMP3DownloaderPlugin: Version: AmazonMP3DownloaderPlugin 1.0.17 - SDK 10.4 Support
  Silverlight: Version: 4.0.60831.0 Support
  iPhotoPhotocast: Version: 7.0
Safari Extensions: ℹ️
  Amazon Shopping Assistant
  Wallet
  Evernote Web Clipper
  Disconnect
  SlickSavings
  Ebay Shopping Assistant
  1Password
  Save to Pocket
  Searchme
3rd Party Preference Panes: ℹ️
  Flash Player  Support
  Growl  Support
  Java  Support
  MacFUSE  Support
  MediaLink  Support
  MusicManager  Support
  Perian  Support
  StuffIt AVR  Support
Time Machine: ℹ️
  Skip System Files: NO
  Mobile backups: OFF
  Auto backup: YES
  Volumes being backed up:
  Macintosh HD: Disk size: 999.35 GB Disk used: 497.67 GB
  Destinations:
  Time Machine 1TB [Local]
  Total size: 999.83 GB
  Total number of backups: 69
  Oldest backup: 2014-05-15 14:54:37 +0000
  Last backup: 2014-11-16 05:00:10 +0000
  Size of backup disk: Too small
  Backup size 999.83 GB < (Disk used 497.67 GB X 3)
Top Processes by CPU: ℹ️
      17% Backup to Flickr for iPhoto
      4% Safari
      3% WindowServer
      2% Dropbox
      2% coreaudiod
Top Processes by Memory: ℹ️
  1.11 GB Backup to Flickr for iPhoto
  112 MB Safari
  103 MB mds_stores
  86 MB WindowServer
  69 MB com.apple.WebKit.WebContent
Virtual Memory Information: ℹ️
  685 MB Free RAM
  3.09 GB Active RAM
  1.51 GB Inactive RAM
  1.20 GB Wired RAM
  132.97 GB Page-ins
  951 MB Page-outs

You need to get rid of MemoryClean as that is one of the very bad programs to run...that takes a lot of memory itself and actually does nothing the Mac OS X does itself.
The Mac OS X versions from Lion to Mavericks grab most of the memory in the system, and then allocate the memory as needed.  That makes programs like MemoryClean and CleanMyMac THINK there is not free memory when there actually is.
It is more productive to look at Activity Monitor, Memory and see what is shown at the bottom of the pane...the Memory Pressure is the most important part.  As long as that is green you are fine.  If yellow you are pushing things.
For a system running Yosemite, which has a better memory allocation algorithm than Mavericks:

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      Mac mini (Late 2012) (Verified)
      Mac mini - model: Macmini6,2
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      8 GB RAM
    Video Information: ?
      Intel HD Graphics 4000 - VRAM: (null)
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      Mobile backups: OFF
      Auto backup: YES
      Volumes being backed up:
      Destinations:
      My Book for Mac [Local] (Last used)
      Total size: 2 
      Total number of backups: 59
      Oldest backup: 2014-02-12 15:44:15 +0000
      Last backup: 2014-08-11 13:36:13 +0000
      Size of backup disk: Excellent
      Backup size 2  > (Disk size 0 B X 3)
      Time Machine details may not be accurate.
      All volumes being backed up may not be listed.
    Top Processes by CPU: ?
          3% WindowServer
          2% coreaudiod
          1% fontd
          1% Boom
          0% Mail
    Top Processes by Memory: ?
      98 MB Mail
      74 MB com.apple.WebKit.WebContent
      57 MB Finder
      49 MB WindowServer
      49 MB Safari
    Virtual Memory Information: ?
      2.38 GB Free RAM
      1.04 GB Active RAM
      3.78 GB Inactive RAM
      807 MB Wired RAM
      227 MB Page-ins
      0 B Page-outs

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