IMac running 10.7.3 stuck on rainbow wheel right after desktop launches and google chrome trying to restore a previous browsing session

Hello All - thanks in advance for your help with this.
The problem I'm encountering is on an iMac 24" from 2008, Intel Core 2Duo 1.3 GHz processor.  I'm running 10.7.3 but have yet to install the client combo update.
My computer would not wake from sleep this morning after having been left on all night.  The last two apps I had been running last night before this morning's freeze up were Google Chrome and iTunes.  I restarted the computer and noticed at the login screen that one of the login accounts that is normally set up for use had disappeared.  Once I logged in to my account, which had not disappeared, and arrived at the desktop, Chrome automatically tried to relaunch and restore the previous session with a note indicating that the browser had not been quit properly.
iTunes was running as well but had no functionality - non responsive to mouse click commands, etc.  About thirty seconds later the rainbow wheel appeared and began spinning.
Tried force quitting both applications applications respectively but the finder was non-responsive as well.  The dock would pop up when moused over but I was not permitted to select any of the icons.  Restarted the computer and essentially the same thing occurred but I was able to quit out of iTunes this time before the rainbow wheel started.
Tried restarting with all peripheral hardware disconnected.  No change.  Tried booting up in safe mode - didn't work.  Rebooted in disk utility mode - ran disk verification and was told all was well.  Ran permissions verifications and was told there were problems.  Repaired the permissions issues successfully.  Rebooted again but same issue with desktop/apps freezing up.  Rebooted into Disk Utility mode and tried a reinstall of lion - reinstall successul but upon normal reboot desktop still frozen once I launched Chrome and attempted to get to apple site to download the 10.7.3 patch.
Tried rebooting in disk utility mode to restore from a time machine back up - the external hard drive where my back ups are stored did not appear as a restore source even though I had reconnected the USB cable. 
I then rebooted again into disk utility mode and tried to use safari to navigate to the apple site and download the 10.7.3 client combo update.  No dice - received error messages saying the download could not be completed because there was insufficient memory available.
Called Apple - rep said I should take the computer in to the store - refused as of the time of the call because I had already wasted half the day on this and didn't want to flush the remainder down the toilet hanging around at the Apple store.  So much for that - the day is now totally wasted any way.
Another couple of bits of information which may or may not be helpful:
When I'm in disk utility mode the disk image icon at the top of the list of disk images/mounts on the left hand side of the utility window is in red text: 320.07 GB WDC WD320...and the main dialogue box says: "This drive has a hardware problem that can't be repaired.  Back up Data and see Apple dealer for help." One might conclude that my computer is therefore dead...not exactly.  This happened once before after trying to set up a bootcamp partition using XP instead of windows 7.  XP is not supported by Lion but I was trying a work around.  Soon thereafter I upgraded my OS to 10.7.2 (or.3 can't remember) using software updater instead of a full native download from the Apple Support site and the computer went bananas.  After the upgrade I was getting the CUI ???? errors which have since become infamous.  While working with Apple phone support on the CUI issue and using disk utility on that issue, that same red text disc image came up and the note about my hardware having failed as described above.  Apple told me I was cooked and my machine was finished.  They were wrong.  I can't remember what I did but I worked on the problem a bit more and was eventually able to upgrade my OS from the native download and get my machine back in order and runnign fine.
I recently attempted the bootcamp partition (stupidly) work around for XP again without success - last week before all of the latest drama set in.  YES I have learned my lession and will not attempt this again.
So that's what's going on - sorry for the Moby Dick lenght description but I figured the more details available the more likely some one is to know how to fix the problem.
Any thoughts, suggestions, HELP please!!!
Thanks.

Hello All - thanks in advance for your help with this.
The problem I'm encountering is on an iMac 24" from 2008, Intel Core 2Duo 1.3 GHz processor.  I'm running 10.7.3 but have yet to install the client combo update.
My computer would not wake from sleep this morning after having been left on all night.  The last two apps I had been running last night before this morning's freeze up were Google Chrome and iTunes.  I restarted the computer and noticed at the login screen that one of the login accounts that is normally set up for use had disappeared.  Once I logged in to my account, which had not disappeared, and arrived at the desktop, Chrome automatically tried to relaunch and restore the previous session with a note indicating that the browser had not been quit properly.
iTunes was running as well but had no functionality - non responsive to mouse click commands, etc.  About thirty seconds later the rainbow wheel appeared and began spinning.
Tried force quitting both applications applications respectively but the finder was non-responsive as well.  The dock would pop up when moused over but I was not permitted to select any of the icons.  Restarted the computer and essentially the same thing occurred but I was able to quit out of iTunes this time before the rainbow wheel started.
Tried restarting with all peripheral hardware disconnected.  No change.  Tried booting up in safe mode - didn't work.  Rebooted in disk utility mode - ran disk verification and was told all was well.  Ran permissions verifications and was told there were problems.  Repaired the permissions issues successfully.  Rebooted again but same issue with desktop/apps freezing up.  Rebooted into Disk Utility mode and tried a reinstall of lion - reinstall successul but upon normal reboot desktop still frozen once I launched Chrome and attempted to get to apple site to download the 10.7.3 patch.
Tried rebooting in disk utility mode to restore from a time machine back up - the external hard drive where my back ups are stored did not appear as a restore source even though I had reconnected the USB cable. 
I then rebooted again into disk utility mode and tried to use safari to navigate to the apple site and download the 10.7.3 client combo update.  No dice - received error messages saying the download could not be completed because there was insufficient memory available.
Called Apple - rep said I should take the computer in to the store - refused as of the time of the call because I had already wasted half the day on this and didn't want to flush the remainder down the toilet hanging around at the Apple store.  So much for that - the day is now totally wasted any way.
Another couple of bits of information which may or may not be helpful:
When I'm in disk utility mode the disk image icon at the top of the list of disk images/mounts on the left hand side of the utility window is in red text: 320.07 GB WDC WD320...and the main dialogue box says: "This drive has a hardware problem that can't be repaired.  Back up Data and see Apple dealer for help." One might conclude that my computer is therefore dead...not exactly.  This happened once before after trying to set up a bootcamp partition using XP instead of windows 7.  XP is not supported by Lion but I was trying a work around.  Soon thereafter I upgraded my OS to 10.7.2 (or.3 can't remember) using software updater instead of a full native download from the Apple Support site and the computer went bananas.  After the upgrade I was getting the CUI ???? errors which have since become infamous.  While working with Apple phone support on the CUI issue and using disk utility on that issue, that same red text disc image came up and the note about my hardware having failed as described above.  Apple told me I was cooked and my machine was finished.  They were wrong.  I can't remember what I did but I worked on the problem a bit more and was eventually able to upgrade my OS from the native download and get my machine back in order and runnign fine.
I recently attempted the bootcamp partition (stupidly) work around for XP again without success - last week before all of the latest drama set in.  YES I have learned my lession and will not attempt this again.
So that's what's going on - sorry for the Moby Dick lenght description but I figured the more details available the more likely some one is to know how to fix the problem.
Any thoughts, suggestions, HELP please!!!
Thanks.

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