IMac/Yosemite super sluggish

Thanks in advance to all who read and assist!
My system is moving slower and slower these days, especially during Time Machine backups, but also at other times, for reasons I can't figure out.  Here is what EtreCheck says:
Problem description:
System is suddenly slowing down to the point that programs being launched become unresponsive.
EtreCheck version: 2.1.8 (121)
Report generated March 6, 2015 at 11:54:12 AM CST
Download EtreCheck from http://etresoft.com/etrecheck
Click the [Click for support] links for help with non-Apple products.
Click the [Click for details] links for more information about that line.
Hardware Information: ℹ️
    iMac Intel Core 2 Duo (aluminum enclosure) (Mid 2007)
    iMac - model: iMac7,1
    1 2.4 GHz Intel Core 2 Duo CPU: 2-core
    3 GB RAM Upgradeable
        BANK 0/DIMM0
            1 GB DDR2 SDRAM 667 MHz ok
        BANK 1/DIMM1
            2 GB DDR2 SDRAM 667 MHz ok
    Bluetooth: Old - Handoff/Airdrop2 not supported
    Wireless:  en1: 802.11 a/b/g/n
Video Information: ℹ️
    ATI,RadeonHD2600 - VRAM: 256 MB
        iMac 1680 x 1050
System Software: ℹ️
    OS X 10.10.2 (14C109) - Time since boot: 0:20:56
Disk Information: ℹ️
    Hitachi HDT721064SLA360 disk0 : (640.14 GB)
        EFI (disk0s1) <not mounted> : 210 MB
        Macintosh HD (disk0s2) / : 639.28 GB (248.83 GB free)
        Recovery HD (disk0s3) <not mounted>  [Recovery]: 650 MB
USB Information: ℹ️
    Logitech USB Receiver
    Canon MX330 series
    The Neat Company Neat ADF Scanner
    Seagate FreeAgent 500.11 GB
        EFI (disk1s1) <not mounted> : 210 MB
        Ducat (disk1s2) /Volumes/Ducat : 499.76 GB (387.30 GB free)
    Apple Inc. Built-in iSight
    Apple Inc. Bluetooth USB Host Controller
    Apple Computer, Inc. IR Receiver
    Logitech USB Receiver
Firewire Information: ℹ️
    LaCie Hard Drive Quadra 400mbit - 800mbit max
        EFI (disk2s1) <not mounted> : 210 MB
        BigDisk (disk2s2) /Volumes/BigDisk : 2.00 TB (637.78 GB free) - 44 errors
Gatekeeper: ℹ️
    Mac App Store and identified developers
Kernel Extensions: ℹ️
        /Library/Application Support/Roxio
    [not loaded]    com.roxio.TDIXController (1.4) [Click for support]
        /System/Library/Extensions
    [not loaded]    com.wacom.kext.pentablet (5.2.3) [Click for support]
Startup Items: ℹ️
    RetroRun: Path: /Library/StartupItems/RetroRun
    Startup items are obsolete in OS X Yosemite
Launch Agents: ℹ️
    [not loaded]    com.adobe.AAM.Updater-1.0.plist [Click for support]
    [running]    com.adobe.AdobeCreativeCloud.plist [Click for support]
    [not loaded]    com.adobe.CS4ServiceManager.plist [Click for support]
    [not loaded]    com.brother.LOGINserver.plist [Click for support]
    [not loaded]    com.google.keystone.agent.plist [Click for support]
    [not loaded]    com.teamviewer.teamviewer.plist [Click for support]
    [not loaded]    com.teamviewer.teamviewer_desktop.plist [Click for support]
    [failed]    com.wacom.pentablet.plist [Click for support] [Click for details]
    [not loaded]    com.wacom.wacomtablet.plist [Click for support]
Launch Daemons: ℹ️
    [loaded]    com.adobe.fpsaud.plist [Click for support]
    [running]    com.fitbit.galileod.plist [Click for support]
    [not loaded]    com.google.keystone.daemon.plist [Click for support]
    [not loaded]    com.rogueamoeba.hermes.plist [Click for support]
    [loaded]    com.teamviewer.Helper.plist [Click for support]
    [not loaded]    com.teamviewer.teamviewer_service.plist [Click for support]
User Launch Agents: ℹ️
    [loaded]    com.adobe.AAM.Updater-1.0.plist [Click for support]
    [loaded]    com.adobe.ARM.[...].plist [Click for support]
    [loaded]    com.adobe.ARM.[...].plist [Click for support]
    [failed]    com.google.Chrome.framework.plist [Click for support] [Click for details]
    [failed]    com.google.keystone.agent.plist [Click for support] [Click for details]
    [failed]    com.spotify.webhelper.plist [Click for support]
    [failed]    ws.agile.1PasswordAgent.plist [Click for support] [Click for details]
User Login Items: ℹ️
    AdobeResourceSynchronizer    Application Hidden (/Applications/Adobe Reader.app/Contents/Support/AdobeResourceSynchronizer.app)
    Google Drive    Application  (/Applications/Google Drive.app)
    Fitbit Connect Menubar Helper    UNKNOWN  (missing [redacted]ue)
    Box Edit    Application  (/Users/[redacted]/Library/Application Support/Box/Box Edit/Box Edit.app)
    ConnectService    Application  (/Library/Application Support/ArcSoft/Connect Service/ConnectService.app)
Internet Plug-ins: ℹ️
    AdobePDFViewerNPAPI: Version: 11.0.0 - SDK 10.6 [Click for support]
    Flash Player: Version: 16.0.0.305 - SDK 10.6 Cannot contact Adobe
    AdobePDFViewer: Version: 11.0.0 - SDK 10.6 [Click for support]
    LogMeInSafari32: Version: 1.0.730 [Click for support]
    Unity Web Player: Version: UnityPlayer version 3.4.2f3 - SDK 10.5 [Click for support]
    Photo Center Plugin: Version: Photo Center Plugin 1.1.2.2 [Click for support]
    googletalkbrowserplugin: Version: 1.9.2.1599 [Click for support]
    Scorch: Version: 6.2.0 [Click for support]
    iPhotoPhotocast: Version: 7.0 - SDK 10.8
    QuickTime Plugin: Version: 7.7.3
    LogMeInSafari64: Version: 1.0.730 [Click for support]
    FlashPlayer-10.6: Version: 16.0.0.305 - SDK 10.6 [Click for support]
    AdobeAAMDetect: Version: AdobeAAMDetect 2.0.0.0 - SDK 10.7 [Click for support]
    npgtpo3dautoplugin: Version: 0.1.43.4 [Click for support]
    Musicnotes: Version: 1.18.8 [Click for support]
    eMusic: Version: Unknown [Click for support]
    LogMeIn: Version: 1.0.730 [Click for support]
    RhapsodyPlayerEngine: Version: 1.0.0 [Click for support]
    Silverlight: Version: 5.1.20513.0 - SDK 10.6 [Click for support]
    AmazonMP3DownloaderPlugin101750: Version: AmazonMP3DownloaderPlugin 1.0.17 - SDK 10.4 [Click for support]
    npg: Version: 1.0 [Click for support]
    Default Browser: Version: 600 - SDK 10.10
    Flip4Mac WMV Plugin: Version: 2.3.8.1 [Click for support]
    WacomSafari: Version: 1.1.0-6 [Click for support]
    JavaAppletPlugin: Version: 15.0.0 - SDK 10.10 Check version
    WacomNetscape: Version: 1.1.0-6 [Click for support]
User internet Plug-ins: ℹ️
    fbplugin_1_0_3: Version: Unknown [Click for support]
    WebEx: Version: 1.0 [Click for support]
    BrowserPlus_2.9.8: Version: 2.9.8 [Click for support]
    WebEx64: Version: 1.0 - SDK 10.6 [Click for support]
    Box Edit: Version: BoxEdit 1.1.36.0 - SDK 10.0 [Click for support]
Safari Extensions: ℹ️
    1Password
    AdBlock
    Add to Wunderlist
Audio Plug-ins: ℹ️
    DVCPROHDAudio: Version: 1.2
3rd Party Preference Panes: ℹ️
    Application Enhancer  [Click for support]
    BrowserPlus  [Click for support]
    Flash Player  [Click for support]
    Flip4Mac Editcam  [Click for support]
    Flip4Mac WMV  [Click for support]
    Flip4Mac XDCam  [Click for support]
    Growl  [Click for support]
    Logitech Control Center  [Click for support]
    MacFUSE  [Click for support]
    Perian  [Click for support]
Time Machine: ℹ️
    Skip System Files: NO
    Auto backup: YES
    Volumes being backed up:
        Macintosh HD: Disk size: 639.28 GB Disk used: 390.45 GB
        Ducat: Disk size: 499.76 GB Disk used: 112.47 GB
    Destinations:
        BigDisk [Local]
        Total size: 2.00 TB
        Total number of backups: 218
        Oldest backup: 2011-03-02 01:24:40 +0000
        Last backup: 2015-03-06 16:33:27 +0000
        Size of backup disk: Adequate
            Backup size 2.00 TB > (Disk used 502.92 GB X 3)
Top Processes by CPU: ℹ️
         3%    WindowServer
         0%    Creative Cloud
         0%    Activity Monitor
         0%    Google Drive
         0%    galileod
Top Processes by Memory: ℹ️
    155 MB    Google Chrome
    129 MB    Google Chrome Helper
    77 MB    mds_stores
    77 MB    Google Drive
    74 MB    Finder
Virtual Memory Information: ℹ️
    156 MB    Free RAM
    1.35 GB    Active RAM
    1.21 GB    Inactive RAM
    462 MB    Wired RAM
    2.13 GB    Page-ins
    1 MB    Page-outs
Diagnostics Information: ℹ️
    Mar 6, 2015, 11:49:22 AM    /Library/Logs/DiagnosticReports/Adobe InDesign CC 2014_2015-03-06-114922_[redacted].hang
    Mar 6, 2015, 11:33:58 AM    /Users/[redacted]/Library/Logs/DiagnosticReports/GoogleSoftwareUpdateAgent_2015 -03-06-113358_[redacted].crash
    Mar 6, 2015, 11:31:12 AM    /Library/Logs/DiagnosticReports/WacomTabletDriver_2015-03-06-113112_[redacted]. crash
    Mar 6, 2015, 11:29:06 AM    Self test - passed
    Mar 6, 2015, 11:14:31 AM    /Users/[redacted]/Library/Logs/DiagnosticReports/GoogleSoftwareUpdateAgent_2015 -03-06-111431_[redacted].crash
    Mar 6, 2015, 10:15:22 AM    /Users/[redacted]/Library/Logs/DiagnosticReports/GoogleSoftwareUpdateAgent_2015 -03-06-101522_[redacted].crash
    Mar 6, 2015, 09:16:34 AM    /Users/[redacted]/Library/Logs/DiagnosticReports/GoogleSoftwareUpdateAgent_2015 -03-06-091634_[redacted].crash
    Mar 6, 2015, 08:17:45 AM    /Users/[redacted]/Library/Logs/DiagnosticReports/GoogleSoftwareUpdateAgent_2015 -03-06-081745_[redacted].crash
    Mar 6, 2015, 07:19:01 AM    /Users/[redacted]/Library/Logs/DiagnosticReports/GoogleSoftwareUpdateAgent_2015 -03-06-071901_[redacted].crash
    Mar 6, 2015, 06:20:13 AM    /Users/[redacted]/Library/Logs/DiagnosticReports/GoogleSoftwareUpdateAgent_2015 -03-06-062013_[redacted].crash
    Mar 6, 2015, 05:21:24 AM    /Users/[redacted]/Library/Logs/DiagnosticReports/GoogleSoftwareUpdateAgent_2015 -03-06-052124_[redacted].crash
    Mar 6, 2015, 04:22:36 AM    /Users/[redacted]/Library/Logs/DiagnosticReports/GoogleSoftwareUpdateAgent_2015 -03-06-042236_[redacted].crash
    Mar 6, 2015, 03:23:47 AM    /Users/[redacted]/Library/Logs/DiagnosticReports/GoogleSoftwareUpdateAgent_2015 -03-06-032347_[redacted].crash
    Mar 6, 2015, 02:24:58 AM    /Users/[redacted]/Library/Logs/DiagnosticReports/GoogleSoftwareUpdateAgent_2015 -03-06-022458_[redacted].crash
    Mar 6, 2015, 01:26:14 AM    /Users/[redacted]/Library/Logs/DiagnosticReports/GoogleSoftwareUpdateAgent_2015 -03-06-012614_[redacted].crash
    Mar 6, 2015, 12:27:30 AM    /Users/[redacted]/Library/Logs/DiagnosticReports/GoogleSoftwareUpdateAgent_2015 -03-06-002730_[redacted].crash
    Mar 5, 2015, 11:28:45 PM    /Users/[redacted]/Library/Logs/DiagnosticReports/GoogleSoftwareUpdateAgent_2015 -03-05-232845_[redacted].crash
    Mar 5, 2015, 10:29:55 PM    /Users/[redacted]/Library/Logs/DiagnosticReports/GoogleSoftwareUpdateAgent_2015 -03-05-222955_[redacted].crash
    Mar 5, 2015, 09:31:11 PM    /Users/[redacted]/Library/Logs/DiagnosticReports/GoogleSoftwareUpdateAgent_2015 -03-05-213111_[redacted].crash
    Mar 5, 2015, 08:32:27 PM    /Users/[redacted]/Library/Logs/DiagnosticReports/GoogleSoftwareUpdateAgent_2015 -03-05-203227_[redacted].crash
    Mar 5, 2015, 07:33:44 PM    /Users/[redacted]/Library/Logs/DiagnosticReports/GoogleSoftwareUpdateAgent_2015 -03-05-193344_[redacted].crash
    Mar 5, 2015, 06:34:59 PM    /Users/[redacted]/Library/Logs/DiagnosticReports/GoogleSoftwareUpdateAgent_2015 -03-05-183459_[redacted].crash
    Mar 5, 2015, 05:36:15 PM    /Users/[redacted]/Library/Logs/DiagnosticReports/GoogleSoftwareUpdateAgent_2015 -03-05-173615_[redacted].crash
    Mar 5, 2015, 04:37:25 PM    /Users/[redacted]/Library/Logs/DiagnosticReports/GoogleSoftwareUpdateAgent_2015 -03-05-163725_[redacted].crash
    Mar 5, 2015, 03:38:35 PM    /Users/[redacted]/Library/Logs/DiagnosticReports/GoogleSoftwareUpdateAgent_2015 -03-05-153835_[redacted].crash
    Mar 5, 2015, 02:39:44 PM    /Users/[redacted]/Library/Logs/DiagnosticReports/GoogleSoftwareUpdateAgent_2015 -03-05-143944_[redacted].crash
    Mar 5, 2015, 01:40:23 PM    /Users/[redacted]/Library/Logs/DiagnosticReports/GoogleSoftwareUpdateAgent_2015 -03-05-134023_[redacted].crash
    Mar 5, 2015, 12:41:31 PM    /Users/[redacted]/Library/Logs/DiagnosticReports/GoogleSoftwareUpdateAgent_2015 -03-05-124131_[redacted].crash
    Mar 5, 2015, 11:42:22 AM    /Users/[redacted]/Library/Logs/DiagnosticReports/GoogleSoftwareUpdateAgent_2015 -03-05-114222_[redacted].crash
    Mar 5, 2015, 10:43:12 AM    /Users/[redacted]/Library/Logs/DiagnosticReports/GoogleSoftwareUpdateAgent_2015 -03-05-104312_[redacted].crash
    Mar 5, 2015, 10:09:24 AM    /Users/[redacted]/Library/Logs/DiagnosticReports/dynamiclinkmanager_2015-03-05- 100924_[redacted].crash
    Mar 5, 2015, 09:44:08 AM    /Users/[redacted]/Library/Logs/DiagnosticReports/GoogleSoftwareUpdateAgent_2015 -03-05-094408_[redacted].crash
    Mar 5, 2015, 09:04:45 AM    /Users/[redacted]/Library/Logs/DiagnosticReports/GoogleSoftwareUpdateAgent_2015 -03-05-090445_[redacted].crash
    Mar 5, 2015, 09:03:12 AM    /Library/Logs/DiagnosticReports/WacomTabletDriver_2015-03-05-090312_[redacted]. crash
    Mar 4, 2015, 07:57:26 PM    /Users/[redacted]/Library/Logs/DiagnosticReports/GoogleSoftwareUpdateAgent_2015 -03-04-195726_[redacted].crash
    Mar 4, 2015, 06:58:29 PM    /Users/[redacted]/Library/Logs/DiagnosticReports/GoogleSoftwareUpdateAgent_2015 -03-04-185829_[redacted].crash
    Mar 4, 2015, 05:59:48 PM    /Users/[redacted]/Library/Logs/DiagnosticReports/GoogleSoftwareUpdateAgent_2015 -03-04-175948_[redacted].crash
    Mar 4, 2015, 05:57:34 PM    /Library/Logs/DiagnosticReports/WacomTabletDriver_2015-03-04-175734_[redacted]. crash
    Mar 4, 2015, 03:36:04 PM    /Users/[redacted]/Library/Logs/DiagnosticReports/GoogleSoftwareUpdateAgent_2015 -03-04-153604_[redacted].crash
    Mar 4, 2015, 02:36:57 PM    /Users/[redacted]/Library/Logs/DiagnosticReports/GoogleSoftwareUpdateAgent_2015 -03-04-143657_[redacted].crash
    Mar 4, 2015, 01:37:55 PM    /Users/[redacted]/Library/Logs/DiagnosticReports/GoogleSoftwareUpdateAgent_2015 -03-04-133755_[redacted].crash
    Mar 4, 2015, 12:38:47 PM    /Users/[redacted]/Library/Logs/DiagnosticReports/GoogleSoftwareUpdateAgent_2015 -03-04-123847_[redacted].crash
    Mar 4, 2015, 11:39:52 AM    /Users/[redacted]/Library/Logs/DiagnosticReports/GoogleSoftwareUpdateAgent_2015 -03-04-113952_[redacted].crash
    Mar 4, 2015, 10:40:55 AM    /Users/[redacted]/Library/Logs/DiagnosticReports/GoogleSoftwareUpdateAgent_2015 -03-04-104055_[redacted].crash
    Mar 4, 2015, 09:41:52 AM    /Users/[redacted]/Library/Logs/DiagnosticReports/GoogleSoftwareUpdateAgent_2015 -03-04-094152_[redacted].crash
    Mar 4, 2015, 08:42:03 AM    /Users/[redacted]/Library/Logs/DiagnosticReports/GoogleSoftwareUpdateAgent_2015 -03-04-084203_[redacted].crash
    Mar 4, 2015, 07:42:50 AM    /Users/[redacted]/Library/Logs/DiagnosticReports/GoogleSoftwareUpdateAgent_2015 -03-04-074250_[redacted].crash
    Mar 4, 2015, 06:44:03 AM    /Users/[redacted]/Library/Logs/DiagnosticReports/GoogleSoftwareUpdateAgent_2015 -03-04-064403_[redacted].crash
    Mar 4, 2015, 05:45:17 AM    /Users/[redacted]/Library/Logs/DiagnosticReports/GoogleSoftwareUpdateAgent_2015 -03-04-054517_[redacted].crash
    Mar 4, 2015, 04:46:32 AM    /Users/[redacted]/Library/Logs/DiagnosticReports/GoogleSoftwareUpdateAgent_2015 -03-04-044632_[redacted].crash
    Mar 4, 2015, 03:47:43 AM    /Users/[redacted]/Library/Logs/DiagnosticReports/GoogleSoftwareUpdateAgent_2015 -03-04-034743_[redacted].crash
    Mar 4, 2015, 02:48:54 AM    /Users/[redacted]/Library/Logs/DiagnosticReports/GoogleSoftwareUpdateAgent_2015 -03-04-024854_[redacted].crash
    Mar 4, 2015, 01:50:05 AM    /Users/[redacted]/Library/Logs/DiagnosticReports/GoogleSoftwareUpdateAgent_2015 -03-04-015005_[redacted].crash
    Mar 4, 2015, 12:51:16 AM    /Users/[redacted]/Library/Logs/DiagnosticReports/GoogleSoftwareUpdateAgent_2015 -03-04-005116_[redacted].crash
    Mar 3, 2015, 11:52:21 PM    /Users/[redacted]/Library/Logs/DiagnosticReports/GoogleSoftwareUpdateAgent_2015 -03-03-235221_[redacted].crash
    Mar 3, 2015, 10:53:33 PM    /Users/[redacted]/Library/Logs/DiagnosticReports/GoogleSoftwareUpdateAgent_2015 -03-03-225333_[redacted].crash
    Mar 3, 2015, 09:54:44 PM    /Users/[redacted]/Library/Logs/DiagnosticReports/GoogleSoftwareUpdateAgent_2015 -03-03-215444_[redacted].crash
    Mar 3, 2015, 08:55:55 PM    /Users/[redacted]/Library/Logs/DiagnosticReports/GoogleSoftwareUpdateAgent_2015 -03-03-205555_[redacted].crash
    Mar 3, 2015, 07:57:06 PM    /Users/[redacted]/Library/Logs/DiagnosticReports/GoogleSoftwareUpdateAgent_2015 -03-03-195706_[redacted].crash
    Mar 3, 2015, 06:58:17 PM    /Users/[redacted]/Library/Logs/DiagnosticReports/GoogleSoftwareUpdateAgent_2015 -03-03-185817_[redacted].crash
    Mar 3, 2015, 05:59:26 PM    /Users/[redacted]/Library/Logs/DiagnosticReports/GoogleSoftwareUpdateAgent_2015 -03-03-175926_[redacted].crash
    Mar 3, 2015, 05:00:31 PM    /Users/[redacted]/Library/Logs/DiagnosticReports/GoogleSoftwareUpdateAgent_2015 -03-03-170031_[redacted].crash
    Mar 3, 2015, 04:01:40 PM    /Users/[redacted]/Library/Logs/DiagnosticReports/GoogleSoftwareUpdateAgent_2015 -03-03-160140_[redacted].crash
    Mar 3, 2015, 03:02:36 PM    /Users/[redacted]/Library/Logs/DiagnosticReports/GoogleSoftwareUpdateAgent_2015 -03-03-150236_[redacted].crash
    Mar 3, 2015, 02:03:36 PM    /Users/[redacted]/Library/Logs/DiagnosticReports/GoogleSoftwareUpdateAgent_2015 -03-03-140336_[redacted].crash
    Mar 3, 2015, 01:04:48 PM    /Users/[redacted]/Library/Logs/DiagnosticReports/GoogleSoftwareUpdateAgent_2015 -03-03-130448_[redacted].crash
    Mar 3, 2015, 12:06:01 PM    /Users/[redacted]/Library/Logs/DiagnosticReports/GoogleSoftwareUpdateAgent_2015 -03-03-120601_[redacted].crash

It appears that the Google software may be the culprit.  It's know to slow down performance.  I'd remove the Google software and only use Google Drive when you need it if you must.  Remove it from the User Log in Items.  If you don't want to use Safari give Firefox a try.  It's much better than Chrome and more secure.
You're not having memory issues as seem with the size of Pageouts you're getting but 3 GB of RAM iis marginal.  Your model can utilize up to 6 GB of memory.  You can replace the 1 GB module with a 4 GB module from Crucial.com or otherworldcomputing.com and see an increase in performance.
Make sure your Wacom tablet software is up to date.

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