Indesign CS6 acting strange at times

Question

I am not loving Indesign CS6. Not because of it's functionality but because it acts strangely. When I quit it, sometimes it takes forever to quit and you start wondering if it is going to, sometimes it says it's closed but the tabbed windows still remain in view only grayed out with the beachball spinning. Eventually it goes away but it is disturbing. anyone know why?
Another thing is that when I change a font size, it will look like it changed but still have the after image of the previous size. Irritating.
One more, and I've had this problem for all of the last versions since I think cs4. When I try to replace a pdf with a current version, (unless I have restarted my computer since the last time I created it,) it tells me that I don't haver permisson or that file may be in use. I end up going to the pdf and trashing it physically. Not very efficient.
I know there are 3 issues but I've only had it for a couple of months at best.
The first issue is the most disturbing.
Mountain Lion 10.8.2, 8 gb memory, processor 3.06 ghz intel

Answer 1

Again, please remove your auto-signature when replying by email.
Let's try a couple of diagnostic experiments, please.
First, create a new user account onthe mac and log in with that and tell us if there is a change in behavior in ID.
Second, try starting in with extensions disabled by holding down the Shift key while booting the Mac. Does that make a difference?
Do you run any sort of utilities -- anti-virus, Mac Keeper, etc.?