Indesign cs6 wont open files

When I attempt to open a .indd file the file will not open and it creates 1000's of temp file in the foldere the files resides. Indesign itself open however. This has only started happening.

Operating System?
How do you open the file? Does this happen with all files? Can you create a new file and save it? Will it reopen?
Where are the files stored?
Does it happen if you create a new user account and log in on that?

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