Installed 10.5.4 and can't launch iSync

Following installation I've just launched iSync and get a dialogue box with the message: "*iSync can't be launched* SyncServices: Can't connect to the sync server: NSInvalidReceivePortException: connection went invalid while waiting for a reply ((null))"
I can't find any assistance for the problem, can anyone help me please

I have tried everything suggested here and my problem remained. I also tried the advice documented here: [http://support.apple.com/kb/TS1627?viewlocale=enUS&locale=enUS] to reset Sync Services.
I finally talked to a very helpful young man at Apple Support, who listened to my story and directed me to take the following action:
Move the SyncServices folder located at ~/Library/Application Support/SyncServices to the desktop
Trash all the caches in ~/Library/Caches
Restart machine (with fingers crossed)
All now seems well and after I'll shortly trash the SyncServices folder sat on the desktop.
I didn't have your issues with lost calendars or scrambled address book contacts but assuming that you're using .Mac you can put this right once you get syncing up and running assuming that you've got clean data (calendars and contacts) on the .Mac server

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