Installed OSX update and apps won't open

I just installed the latest OS-X update and now only Safari will open. I can't run Software update to reload the update. Can someone help me.
Thank you!

Could you verify the operating system level you're talking about. The latest update is OS X 10.7.4 however your post says 10.5.4.
Software Update will not reload something once it's downloaded. You can go to the Apple download site at http://support.apple.com/downloads/ and manually download whatever you need.

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