Installed v8 and now itunes won't open

I upgraded to V 8 and now itunes won't open. Saying my audio configuration not right. Anyone know how to fix this?

I always backup and archive any and all versions I've used and downloaded, or at least until I feel safe with the current version.
Setting a backup also lets a system be restored to prior point in time.
http://www.apple.com/support/itunes/
Audio playback performance issues -
http://docs.info.apple.com/article.html?artnum=93610
http://support.apple.com/kb/TS1386
Troubleshooting iTunes
http://docs.info.apple.com/article.html?artnum=302856

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