Intermittent problem - CS5 document opens grey when starting InDesign

Users PC specs - Windows 7, dual core processor, 1+ GBs of ram (most cases 2+ GB), InDesign CS5.
(200+ InDesign users)
I have had several users complain about documents opening completely grey. The whole document, including text is greyed out. The only thing you can see is outlines of frames. It does not happen all of the time, and usually restarting InDesign solves the problem. I know for a fact it is not a display performance problem where the user has their display performance set to "fast". It is the whole document that is grey and not just the images.
We have tried deleting preferences, uninstalling/reinstalling InDesign, all with no luck. One user has this happen several times on a daily basis.
If anyone has any available information on what might be causing this issue, it would be greatly appreciated!
Thanks!

I have some updates to this problem -
Attempted resolutions -
Patch 7.0.3 has been applied
Drivers have been updated
Bios has been updated
ID CS5 has been removed and reinstalled
Preferences have been deleted
So far, none of these have helped resolve the problem. I've been told that the application crashes 2 out of 3 times when opening a document. InDesign only crashes when opening a document though, not when launching the application alone. This does not happen on a specific document.
There is also an application error recorded in the event log when this happens -
Faulting application name:InDesign.exe, version: 7.0.3.535 time stamp: 0x4ca67222
Faulting module name: Public.dll, version: 7.0.3.535, time stamp: 0x4ca671ad
Exception code: 0xc0000005
This is what InDesign looks like before it actually crashes -

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12/28/13 10:12:37:583 | [ERROR] | | OOBE | DE | | | | 118499 | DF037: Unable to delete directory "/Library/Application Support/Adobe/Adobe PDF/Settings". Check and correct folder & parent directory permissions and then try again.(Seq 10)
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12/28/13 10:12:37:586 | [ERROR] | | OOBE | DE | | | | 118499 | DF037: Unable to delete directory "/Library/Application Support/Adobe/Adobe PDF". Check and correct folder & parent directory permissions and then try again.(Seq 12)
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Intermittent problem - CS5 document opens grey when starting InDesign

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