IPad 2 shuts down any app trying to open a large PDF (40mb)

Hi,
Im trying to get my IPad to display large PDF files from my PC (Windows 7 64bit).  Im using a combination of WD 2 go linked to my NAS (My Book Live with up to date firmware) and also Goodreader.
Everytime I try and open the PDF file both apps close down.  Ive have this problem with the native PDF reader on the iPad, Ibooks and dropbox.
Does the IPad have a limitation on the size of PDF than can be imported and displayed?
My Iphone 4 does the same by the way.
Any ideas??
PS, I joined the apple support community in order to write this post - never had to do that before so Im at the point of giving up unless someone knows something I dont!

Ok, first I should mention I may make $ if you click the link below and purchase items.
The issue with most general PDFs reader/viewers is they assume you have a paper size of 8.5 by 11.5 inches and a few hundred pages. They are not designed to work with thousands of pages, say medical text books of 8,000 pages. Nor  do they work well if the page size is measured in meters or yard. They either crash or scrolling is so painful you give up.
Dealing with thoses issues are hard, anyway I try to as my son who is an engineer complained no app could open his engineering drawings, and Dad can you fix that?
http://itunes.apple.com/WebObjects/MZStore.woa/wa/viewSoftware?id=409408178&mt=8

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    ☞ A web site offers free content such as video or music, but to use it you must install a “codec,” “plug-in,” "player," "downloader," "extractor," or “certificate” that comes from that same site, or an unknown one.
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