Iphone 3gs device cannot start with latest itunes.

I downloaded the latest itunes in my desktop. When I tried to connect my iphone 3gs it says iphoe cannot be used because apple mobile device is not started. I have restarted my system after download, but i don't know what went wrong. My iphone was working perfectly & it's software version is 4.3. Can someobody help me pls.

This is a reasonably common error on a PC when there is a problem with either a USB device, your USB cables or hardware, or the system drivers.
In a case where, as you say, the device works properly with other computers, the problem is more likely to be with the hardware or drivers on the computer you're trying to connect to.
See this site for some hints:
http://www.pchell.com/hardware/usbcode10.shtml
I found it via a web search; I don't have any connection to that site.
The good news is that your iPhone is probably fine.

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