IPhone 4 Does not respond

My iPhone does not respond anymore.
The screen is black and in the middle is a white circle made up of white lines. Similar to sending an email.
I can not turn it off or conect it to my PC Problem code: 0XE8000065
The on/off button does not work either.
Is there anything I can do??

Cheers. After holding it down for the 30 seconds it turned off. Afterwards it started just like before and I didn't lose any apps or pictures......which was good as I'd just taken 100 pictures of my wedding on Saturday.
Thanks once again.

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